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pentobarbital will minimize the level or result of eltrombopag by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Observe.benzhydrocodone/acetaminophen and pentobarbital equally raise sedation. Keep away from or Use Alternate Drug. Limit use to people for whom different therapy alternatives are inadequate
Pursuing oral or parenteral administration, barbiturates commonly cross the placental barrier and so are distributed during fetal tissues with maximum concentrations present in the placenta, fetal liver, and Mind; fetal blood degrees tactic maternal blood stages adhering to parenteral administration
pentobarbital will lessen the extent or impact of cobimetinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Steer clear of coadministration. Sturdy or average CYP3A inducers may possibly minimize cobimetinib systemic publicity by >80% and reduce its efficacy.
Observe Carefully (1)pentobarbital will decrease the extent or impact of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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pentobarbital will lessen the level or impact of etravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the level or outcome of ritonavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
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pentobarbital will decrease the level or outcome of conjugated estrogens, vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lower the extent or outcome of quinine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.
pentobarbital will lower the extent or result of dapsone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.
pentobarbital will decrease the extent or impact of irinotecan liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lower the extent or outcome of efavirenz by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.